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Boundless Bio Announces Presentations at Two January Conferences

January 7, 2020 GMT

SAN DIEGO--(BUSINESS WIRE)--Jan 7, 2020--

Boundless Bio, a company interrogating and targeting extrachromosomal DNA (ecDNA) in aggressive cancers, today announced presentations at the following upcoming conferences:

About ecDNA

Extrachromosomal DNA, or ecDNA, are large circles of DNA containing genes that are outside the cells’ chromosomes and can make many copies of themselves. ecDNA can be rapidly replicated within the cell, causing high numbers of oncogene copies, a trait that can be passed to daughter cells in asymmetric ways during cell division. Cells have the ability to upregulate or downregulate ecDNA and resulting oncogenes to ensure survival under selective pressures, including chemotherapy or radiation, making ecDNA one of cancer cells’ primary mechanisms of recurrence and treatment evasion. ecDNA are rarely seen in healthy cells but are found in many solid tumor cancers. They are a key driver of the most aggressive and difficult-to-treat cancers, specifically those characterized by high copy number amplification of oncogenes.

About Boundless Bio

Boundless Bio is a biotechnology company focused on interrogating a novel area of cancer biology, extrachromosomal DNA (ecDNA), to deliver transformative therapies to patients with previously intractable cancers. For more information, visit www.boundlessbio.com.

View source version on businesswire.com:https://www.businesswire.com/news/home/20200107005220/en/

CONTACT: Sarah Sutton

Glover Park Group

ssutton@gpg.com

202-337-0808Danielle Cantey

Glover Park Group

dcantey@gpg.com

202-337-0808

KEYWORD: UNITED STATES NORTH AMERICA CALIFORNIA

INDUSTRY KEYWORD: HEALTH BIOTECHNOLOGY GENETICS ONCOLOGY RESEARCH SCIENCE GENERAL HEALTH

SOURCE: Boundless Bio

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PUB: 01/07/2020 08:30 AM/DISC: 01/07/2020 08:30 AM

http://www.businesswire.com/news/home/20200107005220/en