Caleb Williams threw for 322 yards and accounted for five touchdowns, Marshawn Lloyd ran for 154 yards and No. 5 Southern California outlasted Arizona State’s upset bid with a 42-28 win.
Brayden Schager passed for a touchdown and ran for another and Matthew Shipley kicked a 24-yard field goal as time expired to help Hawaii erase a 14-point halftime deficit and beat New Mexico State 20-17.
Mikey Keane threw three touchdown passes and Fresno State scored a TD on each of its first seven possessions to help the Bulldogs beat Kent State 53-10.
Justice Jackson and Michael Wortham each ran for a touchdown and Marlon Jones Jr. returned an interception for a TD to help Eastern Washington beat UC Davis 27-24 in a Big Sky Conference opener.
Freshman Jai’Den “Jet” Thomas tied the program record with four rushing touchdowns to help UNLV beat UTEP 45-28 and earn first-year coach Dave Odom’s first road win.
Redshirt senior Jordan McCloud accounted for a career-high six touchdowns, including a 74-yard pass to Reggie Brown that capped the scoring, and James Madison held off a furious rally by Utah State to win 45-38.
Zeon Chriss passed for 249 yards and a touchdown and ran for two more TDs, Patrick Mensah returned an interception for a score, and Louisiana held off Buffalo for a 45-38 win.
Justin Miller threw two touchdown passes and Southern Utah scored three unanswered touchdowns in the second half to pull away from Western Illinois, 37-17 in its home opener.
True freshman Jaylen Raynor threw for three touchdowns and ran for two in his first start to lead Arkansas State to a 44-37 win over Southern Mississippi in a Sun Belt Conference opener.
Coulter Cleland threw for two touchdowns, Aaron Maione added two on the ground and Davidson beat NAIA-school St. Andrews 84-6 on Saturday.
Jyran Mitchell rushed for 238 yards and three touchdown and Butler defeated Stetson 28-18 in Pioneer Football League opener.
Robert Coleman threw a pair of first-quarter touchdown passes and Khalan Griffin and Damashja Harris combined to run for 198 yards and a touchdown apiece to help power Lamar to a 38-0 shutout win over unaffiliated Lincoln (CA).
Colby Suits threw for three first-half touchdowns and Darryle Evans had 173 yards on the ground, leading Houston Christian to a 34-19 victory over Southeastern Louisiana.
Corey Fields Jr. passed for 301 yards and three touchdowns to lead South Carolina State to a 31-10 victory over The Citadel.
ShunDerrick Powell ran for 256 yards and a touchdown and Central Arkansas rolled to a 52-17 win over Abilene Christian in a United Athletic Conference opener for both teams.
Irv Mulligan raced 66 yards for a touchdown and Jason Brown threw for a two-point conversion to cement Jackson State’s 22-16 win over Bethune-Cookman in the Tigers’ home opener.
Drake Maye threw for 296 yards and a touchdown and ran for two more scores as No. 17 North Carolina raced past Pittsburgh 41-24.
Kayvon Britten ran for a touchdown early, Ty Rawls returned an interception for a late score and Tarleton held off Southwest Baptist 27-13.
Sam Franklin ran for a career-high 221 yards and two long touchdowns in the fourth quarter and UT Martin dominated the second half for a 37-21 win over North Alabama.
Sean Chambers threw a pair of touchdown passes and ran for two more scores as Montana State routed Weber State 40-0 in a Big Sky Conference opener.
Michael Pratt threw for 190 yards and two touchdowns, the Tulane defense came up with four interceptions, and the Green Wave defeated Nicholls 36-7.
Justin Pegues and Marcus Knight each had a touchdown run in the fourth quarter and Tennessee Tech beat Kennesaw State 17-7.
Reese Poffenbarger accounted for a touchdown in the first and second overtimes to give Albany a 23-17 victory over Morgan State.
Luther Burden III put on a show in his first collegiate game in his hometown catching a career-high 10 passes for a career-best 177 yards to help Missouri beat Memphis 34-27 Saturday night.
Spencer Rattler went 18-of-20 passing for 288 yards and three touchdowns to lead South Carolina to a 37-30 win over Mississippi State.
Chip Trayanum’s 1-yard TD run with a second left to give No. 6 Ohio State a 17-14 victory at No. 9 Notre Dame.
Drew Allar threw for four touchdowns and Penn State’s defense forced four turnovers to lead the seventh-ranked Nittany Lions past No. 24 Iowa 31-0.
Tight end Brock Bowers caught two of Carson Beck’s three touchdown passes, including a 41-yarder that helped No. 1 Georgia overcome a sluggish start, and the Bulldogs beat UAB 49-21.
Josh Kelly had three touchdown receptions, Cameron Ward passed for 404 yards and accounted for five scores, and No. 21 Washington State withstood a late rally to upend No. 14 Oregon State 38-35 in the Pac-12 Conference opener for both teams.
Jakorey Hawkins returned a blocked punt 62 yards for a touchdown with less than two minutes to play, Wrook Brown made an interception at the 6-yard line with 12 seconds left and Wyoming edged Appalachian State 22-19.
Ismail Mahdi rushed for 216 yards and two touchdowns and Texas State scored 35 unanswered points to rally for a 35-24 victory over Nevada.