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Nonalcoholic Steatohepatitis (NASH): 2021 Update Bulletin with Views & Insights from 3 World Leading KOLs; Intercept Pharmaceuticals, Madrigal Pharmaceuticals, and GENFIT -

December 30, 2021 GMT

DUBLIN--(BUSINESS WIRE)--Dec 30, 2021--

The “Nonalcoholic Steatohepatitis (NASH): Update Bulletin” newsletter has been added to’s offering.

This edition presents the views and insights from three world leading key opinion leaders (KOLs) from North America and Europe on a variety of recent events in NASH market, including; Intercept Pharmaceuticals announcing the initiation of the global Phase III REVERSE study to evaluate the efficacy and safety of obeticholic acid (OCA; Ocaliva); Madrigal Pharmaceuticals reports positive top-line data from a Phase II clinical trial assessing MGL-3196 and GENFIT announcing the launch of the first clinical study in paediatric NASH patients to evaluate safety and efficacy of its dual PPARa/d agonist elafibranor.


Business Questions:

  • What are KOL’s current views on obeticholic acid (OCA; Ocaliva) and what would they like to see from longer-term data?
  • How do KOLs view the studies in the cirrhotic NASH patients given safety concerns with Ocaliva in PBC setting?
  • Do KOLs think OCA can meet its primary endpoint in the REVERSE study?
  • How do KOLs think OCA, if approved for NASH, is likely to be priced?
  • How do KOLs rate the potential of Madrigal’s MGL-3196?
  • Where is MGL-3196 best likely to fit into the treatment strategy? What do KOLs say?
  • How do KOLs art the development of elafibranor in paediatric NASH?
  • What concerns do experts have with elafibranor in children?
  • What are KOLs expecting from the Phase III RESOLVE-IT study for elafibranor?

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SOURCE: Research and Markets

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PUB: 12/30/2021 09:03 AM/DISC: 12/30/2021 09:03 AM